OK, so I chickened out last weekened and slept in and told myself Lowe's would be too busy after I got up... I am back in the game this Saturday. I am planning on removing approximately a 3x4 patch of the subfloor and replacing with two sheets of 5/8" ply that has been suggested. I feel confident about cutting the patch so that it will rest over joists and installing blocking at the wall. What kind of glue should I use to stick the two pieces of ply together? I will be using stainless steel screws to install the subfloor and the 2x4 blocking. I also found that there is only 1 screw going through the toilet flange. I believe this is causing the toilet to seem loose and drip. I will be removing the toilet and replacing the wax seal. Is there anything else I should be prepared to do? I have read some things about the subfloor being a structural member and been intimidated and then other times people say not to worry. I doubt the area of rot is close to a load bearing wall, as previously stated, the plumbing wall sits in between two joists. Let me know if you have any more advice, otherwise I am taking care of this on Saturday!