Get quick relief from a sluggish or clogged drain by dropping a few Alka-Seltzer tablets down the drain, followed by a cup of vinegar. Let the mixture work for 5 to 10 minutes, or until you hear the fizzing stop. While the Alka-Seltzer is doing its job, boil a kettle of hot water on the stove, then pour it down the drain to rid your pipes of any remaining residue. (If the clog is stubborn, it might require a second treatment.) The bonus? This process will also alleviate unpleasant drain odors.